J Syst Evol

• Research Article •    

Genetic formation of Sui populations in southwest China

Mingxia Xie1,#, Xingyue Hu2,#, Qiyang Wang1, Zheng Ren1, Yubo Liu1, Meiqing Yang1, Xiaoye Jin1, Xiaomin Yang3, Rui Wang4, Chuan-Chao Wang3,4,5,*, Jiang Huang1,6,*   

  1. 1. Department of Forensic Medicine, Guizhou Medical University, Guiyang, China;
    2. School of International Tourism&Culture, Guizhou Normal University, China;
    3. Department of Anthropology and Ethnology, Institute of Anthropology, Fujian Provincial Key Laboratory of Philosophy and Social Sciences in Bioanthropology, School of Sociology and Anthropology, Xiamen University 361005, Xiamen, China;
    4. State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, China;
    5. Ministry of Education Key Laboratory of Contemporary Anthropology, Department of Anthropology and Human Genetics, School of Life Sciences, Fudan University, Shanghai, 200433 China;
    6. The Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University
    #Equally contributed to this work.
    Corresponding authors. E-mails:Chuan-Chao Wang, wang@xmu.edu.cn;Jiang Huang, mmm_hj@126.com
  • Received:2023-08-29 Accepted:2024-01-06

Abstract: The Sui people living in Guizhou province have a unique ethnic culture and population history due to their long-time isolation from other populations. To investigate the genetic structure of Sui populations in different regions of Guizhou, we genotyped 89 individuals from 4 Sui populations using genome-wide SNP arrays. We analyzed the data using principal component analysis (PCA), ADMIXTURE analysis, f-statistics, qpWave/qpAdm, TreeMix analysis, fineSTRUCTURE, and GLOBETROTTER. We found that Sui populations in Guizhou were genetically homogeneous and had a close genetic affinity with Tai-Kadai-speaking populations, Hmong-Mien-speaking Hmong, and some ancient populations from southern China. The Sui populations could be modeled as an admixture of 33.5%-37.9% of Yellow River Basin farmer-related ancestry and 62.1%-66.5% of Southeast Asian-related ancestry, indicating that the southward expansion of northern East Asian-related ancestry influenced the formation of the Tai-Kadai-speaking Sui people. Future publications of more ancient genomics in southern China could effectively provide further insight into the demographic history and population structure of the Sui people.

Key words: Sui, Gene chips, Ancestry inference, Admixture history, Population substructure